Detalhe da pesquisa
1.
Functional genomics and metabolomics advance the ethnobotany of the Samoan traditional medicine "matalafi".
Proc Natl Acad Sci U S A
; 118(45)2021 11 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34725148
2.
Potential COVID-19 therapeutics from a rare disease: weaponizing lipid dysregulation to combat viral infectivity.
J Lipid Res
; 61(7): 972-982, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32457038
3.
Normalization of Hepatic Homeostasis in the Npc1nmf164 Mouse Model of Niemann-Pick Type C Disease Treated with the Histone Deacetylase Inhibitor Vorinostat.
J Biol Chem
; 292(11): 4395-4410, 2017 03 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28031458
4.
N,N-Bis(glycityl)amines as anti-cancer drugs.
Bioorg Med Chem
; 24(17): 3932-3939, 2016 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27108400
5.
Polyhalogenated Indoles from the Red Alga Rhodophyllis membranacea: The First Isolation of Bromo-Chloro-Iodo Secondary Metabolites.
J Nat Prod
; 79(3): 463-9, 2016 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26756908
6.
A functional, genome-wide evaluation of liposensitive yeast identifies the "ARE2 required for viability" (ARV1) gene product as a major component of eukaryotic fatty acid resistance.
J Biol Chem
; 289(7): 4417-31, 2014 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24273168
7.
Identification and bioactivity of 3-epi-xestoaminol C isolated from the New Zealand brown alga Xiphophora chondrophylla.
J Nat Prod
; 77(6): 1519-23, 2014 Jun 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-24856903
8.
Network Analysis Reveals the Molecular Bases of Statin Pleiotropy That Vary with Genetic Background.
Microbiol Spectr
; : e0414822, 2023 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36946734
9.
Phosphoinositide and redox dysregulation by the anticancer methylthioadenosine phosphorylase transition state inhibitor.
Biochim Biophys Acta Mol Cell Biol Lipids
; 1868(9): 159346, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37301365
10.
Identification and characterization of protein interactions with the major Niemann-Pick type C disease protein in yeast reveals pathways of therapeutic potential.
Genetics
; 225(1)2023 08 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37440478
11.
Loss of subcellular lipid transport due to ARV1 deficiency disrupts organelle homeostasis and activates the unfolded protein response.
J Biol Chem
; 286(14): 11951-9, 2011 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-21266578
12.
An "exacerbate-reverse" strategy in yeast identifies histone deacetylase inhibition as a correction for cholesterol and sphingolipid transport defects in human Niemann-Pick type C disease.
J Biol Chem
; 286(27): 23842-51, 2011 Jul 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-21489983
13.
Phenotypic Screening for Small Molecules that Protect ß-Cells from Glucolipotoxicity.
ACS Chem Biol
; 17(5): 1131-1142, 2022 05 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35439415
14.
Erratum: Publisher Correction: Genetic interaction networks mediate individual statin drug response in Saccharomyces cerevisiae.
NPJ Syst Biol Appl
; 6: 9, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32257384
15.
The complexity of a monogenic neurodegenerative disease: More than two decades of therapeutic driven research into Niemann-Pick type C disease.
Biochim Biophys Acta Mol Cell Biol Lipids
; 1864(8): 1109-1123, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31002946
16.
Evidence for Co-evolutionary History of Early Diverging Lycopodiaceae Plants With Fungi.
Front Microbiol
; 10: 2944, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-32010072
17.
Genetic interaction networks mediate individual statin drug response in Saccharomyces cerevisiae.
NPJ Syst Biol Appl
; 5: 35, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31602312
18.
Ustilago maydis populations tracked maize through domestication and cultivation in the Americas.
Proc Biol Sci
; 275(1638): 1037-46, 2008 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-18252671
19.
Bioactivity-Guided Metabolite Profiling of Feijoa ( Acca sellowiana) Cultivars Identifies 4-Cyclopentene-1,3-dione as a Potent Antifungal Inhibitor of Chitin Synthesis.
J Agric Food Chem
; 66(22): 5531-5539, 2018 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29546758
20.
Domestication of maize, sorghum, and sugarcane did not drive the divergence of their smut pathogens.
Evolution
; 61(2): 388-403, 2007 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17348948